Since then the genus Legionella has expanded, and to date more than 50 different species are described. However, L. This chapter starts with a description of the genus Legionella and the Wnite of these bacteria. We then highlight the epidemiology, clinical features, and the different diagnostic assays and methods available.
In the second part, we focus on the pathogenesis, the virulence factors, and the immune response of the host. In the third section we discuss recent knowledge acquired on genomics, transcriptomics, and the metabolic features of Legionellaand, particularly, we present new insight on comparative genomics, evolution, horizontal gene transfer, and the regulation of the life cycle of L.
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